SCARRING/CICATRICIAL ALOPECIA
Definition and
introduction
A large
number of scalp disorders may destroy the hair follicles and result in scarring
(cicatricial) alopecia. These include diseases that primarily affect the hair
follicles as well as diseases that affect the deeper layers of skin (dermis) and
secondarily cause follicular destruction.
Once
established, cicatricial alopecia is a permanent condition that cannot be reversed
by treatment. For this reason, it is very important to diagnose the hair or
scalp disorders that may produce cicatricial alopecia as soon as possible in
order to start a specific treatment and avoid diffuse follicular destruction.
The
differential diagnosis between the diseases that cause cicatricial alopecia
requires a biopsy (pathological examination). A scalp biopsy is therefore
mandatory in all cases of cicatricial alopecia. The causes are summarized
below:
Follicular diseases
·
Lichen planopilaris
·
Discoid lupus erythematosus
·
Keratosis follicularis spinulosa decalvans
·
Folliculitis decalvans
·
Traction alopecia
Dermal fibrosis
·
Localized scleroderma
·
Radiodermeatitis
·
Pemphigoid
·
Chemical or physical injuries
·
Burns
The
aim of treatment is to avoid further scarring and it is necessary to explain
clearly to the patient that the hair that has been lost will not grow again.
Surgical treatment of cicatricial alopecia includes excision of the scarring
area tissue expansion or hair transplantation.
Lichen planopilaris
Lichen
planolilaris is the most common cause of cicatricial alopecia.
Patients
usually seek medical advice because they have noticed one or several patches of
hair loss. A certain degree of itching is frequently reported. The clinical
examination reveals a variable number of poorly circumscribed bald patches.
Discoid lupus erythematosus
Diagnosis
of ‘discoid lupus erythematosus’ is strongly suggested by the presence of redness
(erythema), prominent hair roots (follicular hyperkeratosis), thinning of skin
(atrophy) and small blood vessels (telangiectasia).
Folliculitis decalvans
This
term is utilized a spectrum of scalp disorders characterized by painful acute
inflammatory changes with or without pustules. Relapsing inflammatory episodes
result in cicatricial alopecia and tufted folliculitis.
Although
the bacteria Staphylococcus aureus
may frequently be isolated from the pustules, folliculitis decalvans is not an infective condition, but
possibly represents an abnormal host response against staphylococcal antigens
or toxins.
Keratosis follicularis spinulosa decalvans (KFSD)
This
inherited condition usually becomes evident in infancy. Follicular papules are
also evident on the eyebrows and cheeks. Alopecia, which is more prominent in
the vertex, usually develops after puberty.
Its severity
varies considerably in different patients.
Brocq pseudoarea
Brocq
pseudoarea is not a separate entity, but represents the cicatricial outcome of
lichen planopilaris. The scalp presents multiple irregular bald atropic areas, but
no signs of inflammation.
Involvement of the beard area has also been
reported.
Localized scleroderma
Localized
scleroderma of the scalp presents as a slowly progressing irregular patch of
hair loss. The skin often shows a certain degree of erythema or pigmentation in
the absence of follicular keratosis or scaling. The patch is often not
completely bald, but presents some vellus or intermediate hairs.
Serve
atrophy with involvement of the hypodermis and muscles is a feature of fronotoparietal
linear scleroderma (‘encoup de sabre’).
Hair transplantation is a good
treatment option for its management. However, there are some factors that
reduce the chances of survival of the implanted grafts:
·
Poor blood supply
·
Fibrosis of deeper layers of skin
The
following are the differences in hair transplant technique in such cases:
1.
The density of the implanted grafts is lesser
2.
A session of trial grafting of 100/150 grafts
can be performed to look for the survival of implanted grafts. If the growth is
good the transplanting the complete bald area can be attempted
3.
The angle of insertion of grafts is less acute
4.
The amount of tumescence anaesthesia
administered is less
5.
Adrenaline is avoided in the anaesthetic
solution.